Na2SO4 and concentrated to dryness.
MeOH dCM ) to provide the pdt as a yellow solid.
After cooling to RT, NaBH3CN (98 mg,.58 mmol) was added to the mixture.
Skip to main content, academia.
The org phase was concentrated and the residue was purified by silica gel column chromatography (6:1.1.1 g, 81 Patent Reference: WO, page 108, (10.3 MB).The reaction was stirred at RT for.The mixture was poured into H2O (10 mL) and extracted with.Ti(iPrO)4 (168 mg,.58 mmol) in, tHF (10 mL) was stirred in a microwave reactor at 100 C for.After stirring 2 h, the reaction mixture was treated with NaBH3CN at 0 C, and stirring was continued for another.PE etOAc ) to provide the product as a yellow solid.
The mixture was extracted with.
The mixture was diluted with H2O (20 mL EtOAc (25 mL and sat aq NaHCO3 (10 mL).